MIT Robot May Accelerate Trials for Stroke Medications From: Medical Design Technology - 02/11/2014 The development of drugs to treat acute stroke or aid in stroke recovery is a multibillion-dollar endeavor that only rarely pays off in the form of government-approved pharmaceuticals. Drug companies spend years testing safety and dosage in the clinic, only to find in Phase III clinical efficacy trials that target compounds have little to no benefit. The lengthy process is inefficient, costly, and discouraging, says Hermano Igo Krebs, a principal research scientist in MIT’s Department of Mechanical Engineering. Now a robot developed by Krebs and his colleagues may help speed up drug development, letting pharmaceutical companies know much earlier in the process whether a drug will ultimately work in stroke patients. In their study, Krebs and his colleagues explored the robot MIT-Manus as a tool for evaluating patient improvement over time. The robot, developed by the team at MIT's Newman Laboratory for Biomechanics and Human Rehabilitation, has mainly been used as a rehabilitation tool: Patients play a video game by maneuvering the robot’s arm, with the robot assisting as needed. Read the entire article at: http://www.mdtmag.com/news/2014/02/mit-robot-may-accelerate-trials-stroke-medications Links: MIT Manus - Robotic Rehabilitation Project (video 5:03) http://www.youtube.com/watch?v=EN5_24biEWU Hermano Igo Krebs http://meche.mit.edu/people/?id=130 Related: Robot-Aided Wrist Rehabilitation after Stroke (with video 0:14) http://newmanlab.mit.edu/robot-aided-wrist-rehabilitation-after-stroke/