Pivotal Study of Medtronic Deep Brain Stimulation Therapy Shows Long-Term
  Reduction in Seizure Rate in Patients with Severe Epilepsy 
From: Medical Device Link - 12/07/2009

Long-term data from an investigational study of Deep Brain Stimulation (DBS)
Therapy for Epilepsy was released this week by Medtronic, Inc. at the
American Epilepsy Society Meeting (AES) in Boston. The results of the study
show improvement over time with median (mid-point) reduction in seizure
frequency of 41 percent at one year, 56 percent at two years, and 68 percent
at three years of DBS therapy, in conjunction with antiepileptic medications,
compared to baseline. Of the original 110 patients who received DBS implants
in the trial, 91 remain active in the study, including some who have received
DBS therapy for more than five years. At the time of this data analysis, 102
patients had completed two years and 57 had completed three years of therapy.
In addition, 14 patients (13 percent) experienced seizure free intervals
ranging from six months to more than four years. 

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