White House, VA conference highlights new technologies for disabled From: VA Research Currents - 11/2004 - page 1 A young quadriplegic controls a cursor on a screen solely through his thoughts. A 72-year-old woman, legally blind since her 30s, reports a new ability to make out shapes. These were among the stunning research results shared by scientists on October 13th and 14th at a Washington, DC, conference sponsored by VA and the White House Office of Science and Technology Policy. The goals of the event were to highlight advances that promise to dramatically improve the lives of Americans with disabilities, and explore ways to make the technology more accessible to consumers. The event was titled "Emerging Technologies in Support of the New Freedom Initiative: Promoting Opportunities for People with Disabilities." The federal New Freedom Initiative, signed into law in 2001, aims to enable those with disabilities to take better advantage of technology and to expand their access to educational, employment and social opportunities. "In a sense, VA does for disabled veterans what the New Freedom Initiative proposes to do for all disabled Americans - remove barriers, develop new technologies, adapt environments, and do all that can be done to allow [them] the full opportunity to seek their dreams," said Pat Ryan, staff director of the Committee on Veterans Affairs of the U.S. House of Representatives and one of the speakers at the event. The first day of the conference featured an overview of state-of-the-art technologies. John P. Donoghue, PhD, a neuroscientist at Brown University, described the "braingate system" - a tiny sensor implanted under the surface of the brain in the area that controls arm movement. The sensor picks up the electrical activity of the brain's neurons. The signals are translated into commands to control an electronic device, such as a cursor. "We've developed computer algorithms that have helped us understand how to convert patterns of this electrical spiking activity into commands," said Donoghue, who is also an investigator with VA's new Providence- based Center for Rebuilding, Regenerating and Restoring Function After Limb Loss. Donoghue said neuromotor prostheses make it possible to "couple the brain to the outside world in paralyzed individuals." He showed a video of a young man with a C4 spinal cord injury, unable to move his arms or legs, who was able to move a cursor without the use of any joystick or other mechanical control. "He is using neurosignals directly from his brain to control that cursor," explained Donoghue. "He is using his thoughts." Among the other presenters was Joseph Rizzo, MD, an associate professor of ophthalmology at Harvard Medical School and director of the Center for Innovative Rehabilitation at the Boston VA. Rizzo described the development of a microelectronic retina implant that could potentially restore vision in cases of age-related macular degeneration or retinitis pigmentosa - both leading causes of blindness among veterans. The system relies on a tiny digital video camera mounted in a pair of glasses. The images from the camera are sent to an ultra-thin layer of electrodes implanted in the retina. The electrodes stimulate the retina’s nerve cells in a pattern resembling the video input, and the image is carried to the brain via the optic nerve. The technology has been tested so far in six humans, including a 72-yearold blind woman who was able to distinguish cloud shapes based on input from the device. Rizzo acknowledged that substantial further research is needed before the system could have clinical applications. "It's already taken almost two decades to get where we are. It's going to take longer to create higher quality vision. So there's a very, very long-term horizon," said Rizzo. Full coverage of the conference, including slide presentations and the results of breakout sessions on topics ranging from health care to transportation, will be available within the near future on the website of VA’s Rehabilitation Research and Development service: http://www.vard.org. White House/VA Conference Emerging Technologies in Support of the New Freedom Initiative: Promoting Opportunities for People with Disabilities October 13-14, 2004 http://www.vard.org/whc2004/index.html