Paraplegic Fitted with Brain Sensor Ushers in Cybernetic Age From: San Francisco Chronicle - 12/05/2004 - P. B1 By: David Ewing Duncan Matthew Nagle is a 25-year-old paraplegic with a sensor implanted directly into his brain that allows him to control a computer as well as an artificial hand by thought. Cyberkinetics Neurotechnology Systems, the human-brain interface's developer, is using Nagle as a test case. Cyberkinetics, co-founded by Brown University neuroscience department director John Donoghue, is the first organization approved by the FDA to run tests on implanted electrode arrays using as many as five disabled human subjects. Nagle's Braingate Neural Interface System is equipped with 100 electrodes implanted above an area of the brain that controls motor activity, and Nagle is plugged into a computer via a fiber-optic cable attached to a cranial node. The computer translates Nagle's neural impulses into commands for moving a cursor or opening and closing the artificial hand. The interface comes from Donoghue's study of how the brain converts thought into physical action by analyzing the mechanics of neuron excitation, and early experiments involved collaboration with University of Utah researchers and the implantation of electrodes into the brain of a primate trained to play computer games using a joystick. Nagle's implant only allows a one-way transmission of Nagle's thoughts to the computer, although there are neural implants that can be triggered or controlled by outside commands--which raises the specter, however unlikely at this point, of mind control. Donoghue's breakthrough also revives visions of being able to download thoughts and consciousness into a computer and transmit them via email, or thought-controlled aircraft for military use; challenges include making the technology less invasive as well as addressing ethical issues. http://www.sfgate.com/cgi-bin/article.cgi?file=/chronicle/archive/2004/12/05/INDUNCAN05.DTL http://www.detnews.com/2004/health/0411/01/a03-315378.htm -- Monkeys, Humans Get Brain-Driven Prostheses From: Discover Magazine - Vol. 26 No. 01 - January 2005 By: Jack Kelley Twentysomething Matthew Nagle sits in front of his computer. Skipping over video games, he selects a desktop icon to lower the volume on his TV, then opens a paint program and sketches a wobbly circle on the monitor. Killing time? Nope, making history. Paralyzed from the neck down and confined to a wheelchair, Nagle controls the computer using only his mind. http://www.discover.com/issues/jan-05/features/neuroscience/brain-driven-prostheses/