Towards a Prosthetic Retina From: IEEE Grid - May 2002 - page 1 Age-related macular degeneration (AMD) is the most common form of severe and irreversible blindness in the US. This proposed research represents a highly interdisciplinary effort between physicians, engineers, and scientists from schools of Medicine, Engineering, and Humanities and Sciences to develop new therapies for AMD and other blinding diseases of the retina. The immediate goal of this research is to develop a neural interface that will connect a digital video camera to individual retinal cells in the eyes of patients with AMD, thus bypassing injured cells. To accomplish this, they are adapting BioMEMs technology to construct an artificial nerve connection that will be fashioned from silicon and upon which the microcircuitry of retinal cells will be regrown. This neural interface would represent a new paradigm in the field of electronic prosthetic retinas that are being developed worldwide. Such a prosthetic would improve the quality of life for the millions of elderly Americans who will develop AMD in the next 20 years. In addition to advancing the treatment of AMD, this method will have wide-reaching applications in spinal cord injuries and in the field of tissue engineering. These bioengineering technologies will help bring basic science discoveries into clinical realities and bridge the gap from bench to bedside. Research in this area is being performed by Harvey A. Fishman, MD, PhD of the Department of Ophthalmology at Stanford University Medical School. He is director of the Stanford Ophthalmic Tissue Engineering Laboratory and a senior research scientist in the Department of Ophthalmology at Stanford University School of Medicine. http://ophthalmology.stanford.edu/researchfishman.htm http://www-med.stanford.edu/school/eye/otel/index.html http://ophthalmology.stanford.edu/faculty/biofish.html